Team Analysis
Overall Reaction

Roster
Outlook
You have some good players that might give you a chance to compete this year, as long as you stay healthy. If you can make a trade that upgrades a starter or two, that would boost your playoff chances.
Playoff Chances
Prediction
QB Analysis

Josh Allen is a strong QB1 for a 12-team league. He should consistently produce high-scoring weeks as your top quarterback.
RB Analysis

Christian McCaffrey is an average RB1 for a 12-team league. Not bad by any means, just not as good as some others. He may help you win you some weeks, but might also have some less-than-stellar performances here and there.
For a 12-team league, Joe Mixon is a pretty good RB2. Barring something unexpected, he should produce well in this role.
WR Analysis

A.J. Brown isn't the best WR1 for a 12-team league, but he might be able to provide you with enough good games to get away with it.
Cooper Kupp isn't that good as a WR2 for a 12-team league, so unless you can upgrade, expect multiple weeks where he lets you down.
TE Analysis

Dallas Goedert isn't the best TE1 for a 12-team league, but he might have just enough good weeks to get away with it.
FLEX Analysis
Your league doesn't start a FLEX.
Compare vs. Average
PK Analysis
Greg Zuerlein isn't the best kicker, but kickers are basically a guessing game.
In general, don't spend much time worrying about kickers. They are too unpredictable. Try to find a kicker on a team with a good offense. And if he's playing in a dome, even better.
DEF Analysis
The San Francisco 49ers are an average defense. They should be fine most weeks unless they have an unfavorable matchup.